Mammalian olfactory receptors
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منابع مشابه
Mammalian Olfactory Receptors
Perception of chemical stimuli from the environment is essential to most animals; accordingly, they are equipped with a complex olfactory system capable of receiving a nearly unlimited number of odorous substances and pheromones. This enormous task is accomplished by olfactory sensory neurons (OSNs) arranged in several chemosensory compartments in the nose. The sensitive and selective responsiv...
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observed with a variety of molecular markers. For examThe main olfactory system of mammals recognizes the ple, the Ga protein Gi2 is expressed at high levels only universe of odorants using as many as a thousand rein apical neurons, while the Ga protein Go is expressed lated G protein–coupled receptors (Buck and Axel, at high levels only in basal neurons (Halpern et al., 1995; 1991). Oddly enou...
متن کاملGenomics of olfactory receptors.
In many species, the sense of smell plays important roles in locating food, detecting predators, navigating, and communicating social information. The olfactory system has evolved complex repertoires of odor receptors (ORs) to fulfill these functions. Through computational data mining, OR repertoires of multiple species were identified, revealing a surprisingly large OR gene family in rodents a...
متن کاملIonotropic Crustacean Olfactory Receptors
The nature of the olfactory receptor in crustaceans, a major group of arthropods, has remained elusive. We report that spiny lobsters, Panulirus argus, express ionotropic receptors (IRs), the insect chemosensory variants of ionotropic glutamate receptors. Unlike insects IRs, which are expressed in a specific subset of olfactory cells, two lobster IR subunits are expressed in most, if not all, l...
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The aim of this study was to explore the possibility of using an archaeal microorganism as a host system for expressing mammalian olfactory receptors (ORs). We have selected the archaeon Haloferax volcanii as a cell host system and one of the most extensively investigated OR, namely I7-OR, whose preferred ligands are short-chain aldehydes, such as octanal, heptanal, nonanal. A novel plasmid has...
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ژورنال
عنوان ژورنال: Frontiers in Cellular Neuroscience
سال: 2009
ISSN: 1662-5102
DOI: 10.3389/neuro.03.009.2009